OptiDose® Design Solution
DRUG DEVELOPMENT & FORMULATION IS SCIENCE.
DOSE DESIGN TO CREATE SUCCESSFUL TREATMENTS IS ART.
Achieving development milestones is critical to progressing your molecule to the clinic, but this doesn’t always translate to successful medicines or better outcomes for patients and stakeholders.
Put our experience to work for you.
Catalent has helped innovators launch thousands of products for over 80 years, so we know what it takes for a therapy to succeed in an increasingly competitive market. We help your molecule progress from oral drug candidate to clinic quickly and efficiently with OptiForm® Solution Suite, solving it’s most complex bioavailability, solubility, and permeability challenges – but we don’t stop there.
We help seamlessly guide your drug through its path to success with OptiDose® Design Solution to help deliver a comprehensive assessment of your molecule, patient, and market.
A DATA-DRIVEN COLLABORATIVE APPROACH
To determine the optimal dose form, Catalent’s team of scientific advisors collaborate with you to review your program background and utilize a set of structured tools to perform a comprehensive evaluation.
By assessing the physicochemical properties of the molecule, ADME/PK/PD characteristics, patient considerations, manufacturability, stability, and market considerations, our team of advisors provide recommendations for a dose form strategy that can help differentiate your product, improve patient acceptance, and turn your science into commercially successful medicine.
Physiochemical – Captures information on material properties of a drug and technology/dose form compatibility
Pharmacokinetics – Captures key pharmacokinetic properties of a drug that deliver efficacy
Patient Considerations – A vision for a product that will meet the needs of the patient
Dose Form Selection & Manufacturability – Recommendations that considers dose form evolution, product differentiation, and speed to market. Plus, a stable drug product and manufacturing process that is efficient and scalable
FEATURES & BENEFITS
Our scientific advisors help you maximize your drug development investment, by identifying risk factors that could affect long-term commercial success and satisfy the needs of your stakeholders and achieve success in the market.
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ADDRESSING PATIENT NEEDS & CHALLENGES
With a wide range of advanced drug delivery technologies able to overcome a variety of drug delivery challenges including dose loading, taste masking, drug release, food effects, and others, Catalent matches stakeholder considerations with these solutions.
Improved API performance
- Solid form screening
- Broadest range of proven solutions to improve bioavailability
Formulation flexibility
- GLP and GMP formulations and test materials for early stage testing
- Seamless transition to stable, scalable finished dose forms
Enhanced therapeutic profiles
- Better absorption
- Faster onset
- Extended release
- Targeted delivery
- Improved therapeutic adherence
- Minimized food effects
- Reduced dose burden
- Reduced dose frequency
Patient experience
- Taste masking
- Better dosing experience for special patient groups (e.g. pediatric, geriatric, psychiatric, veterinary)
- Easier administration
Product differentiation
- Unique technologies to attract prescribers and patient
INTEGRATED SOLUTIONS
BROAD TECHNOLOGY TOOLKIT
- RP Scherer® Softgel Technologies
- OptiShell® gelatin-free capsules
- OptiGel® Bio oral molecule delivery
- OptiGel® Lock abuse resistant technology
- OptiGel® DR delayed release technology
- OptiGel® Mini
- OptiGel® Micro
- Modified Release Technologies
- Zydis® Orally Dissolving Tablet Technology
- Zydis® ODT fast dissolve tablets
- Zydis® Bio oral large molecule delivery
- Stick pack solutions
WHY PARTNER WITH CATALENT?
As a global leader in drug delivery solutions we have the deepest expertise, the broadest offerings, and the most innovative technologies to improve the performance of your products from discovery to market and beyond.