From Lab to Launch: Successful Drug Development Strategies Using Lipid-Based Formulations and Softgels
Summary: Lipid-based formulations (LBFs) enhance the bioavailability of poorly soluble drugs by improving solubilization and absorption in the gastrointestinal tract. They are categorized by their composition of oils, surfactants, and co-solvents. Softgels are ideal for LBF delivery and are compatible with various formulations. Innovations like delayed release and plant-based capsules enhance drug delivery. LBFs with a Quality-by-Design approach offer an efficient route to market for complex drugs.