Versatility of Softgel Technology - The Encapsulation of a Volatile Compound
Summary: Xhale, Inc., a commercial stage medical technology company, had developed the SMART Medication Adherence Monitoring System technology to non-invasively monitor adherence to oral medications. The system is based on detecting 2-butanol, a metabolite of the adherence marker, in patients’ breath and therefore can be used to definitively verify, monitor, and report how and when study participants are taking their medication in real time. By working with Catalent Pharma Solutions, Xhale, Inc. has developed SMART Softgels featuring a special shell to release quickly while still preventing evaporative loss during and after manufacturing.