HPAPI Development and Manufacturing Using Micronization Technology
Summary: The industry continues to shift towards the use of high potent active pharmaceutical ingredients (HPAPIs), which have the potential to offer more effective treatments at smaller doses. For HPAPIs, micronization is a well-established, cost-effective and scalable process to address bioavailability and drug delivery challenges facing certain highly potent oral drugs. While HPAPIs offer significant therapeutic benefits, their potent characteristics present risk so it is critical to take steps to secure the safe handling capabilities necessary to contain, develop and manufacture these compounds.