From Bench to Clinic - Preclinical and First-in-Human Development Strategies
Summary: Crucial and cost-effective factors to consider when transforming a pre-clinical development compound into a first-in-human, early-phase drug candidate. Drug developers must consider many factors when positioning a pre-clinical drug candidate to succeed in first-in-human clinical trials. This executive summary will map out the pre-formulation studies needed to create the best development path for a drug candidate and describe oral and injectable clinical formulation options for short- and long-term success.